Test tubes

Abatacept

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly

In combination with DMARD - monitor as per DMARD

Adalimumab

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly

In combination with DMARD - monitor as per DMARD

Allopurinol

Uric acid: 8 weekly and therapy adjusted by GP until uric acid is <300 umol/1 then annually

FBC, renal and liver function ever 3 months for the first year only

Apremilast

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin checked at Rheumatology appointment

In combination with DMARD - monitor as per DMARD

Azathioprine

FBC weekly for 6 weeks and at 2 and 4 weeks after any dose increases, then monthly if Azathioprine dose remains stable

CRP monthly

LFTs monthly until Azathioprine dose stable then 6 monthly

Baricitinib

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly

In combination with DMARD - monitor as per DMARD

Lipid profile after 12 weeks then as indicated

Benzbromarone

Uric acid: 8 weekly and therapy adjusted by GP until uric acid is <300 umol/1 then annually

LFTs monthly for 1st 6 months then every 6 months

Certolizumab

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly

In combination with DMARD - monitor as per DMARD

Colchicine

Uric acid: 4 weekly and therapy adjusted by GP until uric acid is <300 umol/1 then annually

FBC, renal and liver function ever 3 months for the first year only

Etanercept

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly

In combination with DMARD - monitor as per DMARD

Golimumab

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly

In combination with DMARD - monitor as per DMARD

Leflunomide

FBC, CRP, LFTs monthly for the first 6 months then 2 monthly

BP monthly for 6 months then 2 monthly

Methotrexate

FBC and LFT's 2 weekly for 6 weeks or until dose is stable then monthly for 1st year. 3 monthly thereafter

CRP monthly for first year then 3 monthly

Methotrexate and Leflunomide

FBC and LFT's 2 weekly for 6 weeks or until dose is stable then monthly for 1st year. 2 monthly thereafter

CRP monthly for first year then 2 monthly

BP monthly for first year then 2 monthly

Methotrexate and Sulfasalazine

FBC and LFT's 2 weekly for 6 weeks or until dose is stable then monthly for 1st year. 3 monthly thereafter

CRP monthly for first year then 3 monthly

Mycophenolate mofetil

FBC U&E LFT every week for 4 weeks then twice a month for 2 months then every month in the first year. 3 monthly thereafter

CRP monthly for 1st year then 3 monthly

Myocrisin;

FBC, CRP and Urinalysis at time of each injection. Allowable for FBC and CRP to be one week in arrears

Secukinumab

Monotherapy - U&E, Cr/eGFR, FBC, CRP and LFTs inc albumin at 3 & 6 months after initiation then 6 monthly In combination with DMARD - monitor as per DMARD

Sulfasalazine

FBC, CRP and LFTs 2 weekly for 6 weeks, monthly for 3 months then 3 monthly for 2 years. After that, patient to request FBC, CRP and LFTs prior to clinic appointments only.

Tacrolimus

Renal function and BP ever 2 weeks for 3 months, then monthly

FBC, CRP and LFTs monthly for 3 months then 3 monthly

Lipids and Glucose: 6 monthly

Tacrolimus levels 6 monthly or if abnormal renal function or adverse effects

Tocilizumab

FBC, CRP and LFTs every 4 weeks for 6 months then 3 monthly

Lipid profile after 4-8 weeks then as indicated